听力与言语-语言病理学

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医学伦理学

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  • Odors: implicit memory and performance effects.

    abstract::In order to assess the influence of odors on human performance and implicit memory for odors, 108 subjects completed a variety of tests in weakly scented (jasmine, lavender or odorless) rooms without having been made aware of the odor. After a 30 min interval the subjects were shown slides of different surroundings, i...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/24.3.317

    authors: Degel J,Köster EP

    更新日期:1999-06-01 00:00:00

  • Perception of everyday odors--correlation between intensity, familiarity and strength of hedonic judgement.

    abstract::In this study, 40 Japanese, 44 German and 39 Mexican women were presented with 18 everyday odorants. They were asked to rate them for intensity on a six-point scale from not detectable to very strong, for pleasantness on an 11-point scale from -5, to neutral at 0, to +5, and for familiarity on a six-point scale from c...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/24.2.191

    authors: Distel H,Ayabe-Kanamura S,Martínez-Gómez M,Schicker I,Kobayakawa T,Saito S,Hudson R

    更新日期:1999-04-01 00:00:00

  • The distribution of sugar chains on the vomeronasal epithelium observed with an atomic force microscope.

    abstract::The distribution of sugar chains on tissue sections of the rat vomeronasal epithelium, and the adhesive force between the sugar and its specific lectin were examined with an atomic force microscope (AFM). AFM tips were modified with a lectin, Vicia villosa agglutinin, which recognizes terminal N-acetyl-D-galactosamine...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/24.1.1

    authors: Osada T,Takezawa S,Itoh A,Arakawa H,Ichikawa M,Ikai A

    更新日期:1999-02-01 00:00:00

  • A new method to improve olfactory responses to GC effluents.

    abstract::Biological detectors such as the human nose or an insect antenna represent extremely attractive detectors for gas chromatography (GC) since they are specifically tuned to perceive biologically relevant compounds. However, these detectors are nonlinear, noisy and often perform poorly under standard GC conditions since ...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/23.6.647

    authors: Gouinguené S,de Cruz I,van der Pers J,Wadhams L,Marion-Poll F

    更新日期:1998-12-01 00:00:00

  • The timing of alpha-gustducin expression during cell renewal in rat vallate taste buds.

    abstract::The G protein subunit alpha-gustducin is expressed in a subset of light (Type II) but not in dark (Type I) cells in rat vallate taste buds. The thymidine analogue 5-bromo-2'-deoxyuridine (BrdU) is incorporated into DNA during the S-phase of the cell cycle and can be used to determine the time of origin of a cell. In t...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/23.6.735

    authors: Cho YK,Farbman AI,Smith DV

    更新日期:1998-12-01 00:00:00

  • Olfactory memory: the long and short of it.

    abstract::It has been proposed that memory for odors does not have a short-term (or working) memory system. The distinction between short- and long-term memory in other sensory modalities has been generally supported by three main lines of evidence: capacity differences between the proposed systems, evidence of differential cod...

    journal_title:Chemical senses

    pub_type: 杂志文章,评审

    doi:10.1093/chemse/23.4.433

    authors: White TL

    更新日期:1998-08-01 00:00:00

  • Complex binding interactions between multicomponent mixtures and odorant receptors in the olfactory organ of the Caribbean spiny lobster Panulirus argus.

    abstract::Our study was designed to examine how components of complex mixtures can inhibit the binding of other components to receptor sites in the olfactory system of the spiny lobster Panulirus argus. Biochemical binding assays were used to study how two- to six-component mixtures inhibit binding of the radiolabeled odorants ...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/23.3.269

    authors: Gentilcore LR,Derby CD

    更新日期:1998-06-01 00:00:00

  • Electrophysiological properties of frog olfactory supporting cells.

    abstract::Cells, identified as supporting cells by Lucifer Yellow injection, were recorded from slices of frog olfactory epithelium using patch-clamp recordings. Cell-attached single-channel recordings indicated that the intracellular potential (IP) was -68 +/- 7 mV (n = 22) with 4 mM K+ in the bath ([K+]o). IP was -67 +/- 4 mV...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/23.3.363

    authors: Trotier D

    更新日期:1998-06-01 00:00:00

  • Responses of cultured rat trigeminal ganglion neurons to bitter tastants.

    abstract::The initial steps in taste and olfaction result from the activation by chemical stimuli of taste receptor cells (TRCs) and olfactory receptor neurons (ORNs). In parallel with these two pathways is the chemosensitive trigeminal pathway whose neurons terminate in the oral and nasal cavities and which are activated by ma...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/23.2.125

    authors: Liu L,Simon SA

    更新日期:1998-04-01 00:00:00

  • Current status of antisense DNA methods in behavioral studies.

    abstract::The antisense DNA method has been used successfully to block the expression of specific genes in vivo in neuronal systems. An increasing number of studies in the last few years have shown that antisense DNA administered directly into the brain can modify various kinds of behaviors. These findings strongly suggest that...

    journal_title:Chemical senses

    pub_type: 杂志文章,评审

    doi:10.1093/chemse/23.2.249

    authors: Ogawa S,Pfaff DW

    更新日期:1998-04-01 00:00:00

  • Sensory evaluation of mixtures of maltitol or aspartame, sucrose and an orange aroma.

    abstract::The suitability of Beidler's mixture equation for mixtures of sucrose and maltitol as well as for mixtures of sucrose and aspartame was examined in the presence of an orange aroma. The mean scores for the attribute sweet remained constant for each combination of sucrose and maltitol and for each combination of sucrose...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/23.1.59

    authors: Nahon DF,Roozen JP,de Graaf C

    更新日期:1998-02-01 00:00:00

  • Heterogeneity of odorant-binding proteins in the antennae of Bombyx mori.

    abstract::Different odorant-binding proteins (OBPs) were isolated from total antennal homogenates of male and female Bombyx mori. Proteins were separated according to their isoelectric point by using preparative fast-flow isoelectrofocusing. Odorant-binding proteins were identified in immunoblots by antisera raised against the ...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/22.5.503

    authors: Maida R,Proebstl T,Laue M

    更新日期:1997-10-01 00:00:00

  • Visual and chemical release of feeding behavior in adult rainbow trout.

    abstract::Feeding behavior of adult rainbow trout (Oncorhynchus mykiss) is released by visual and/or chemical stimuli. Detection of either a conditioned visual or a conditioned chemical stimulus creates an excitatory feeding state within the central nervous system which turns on feeding behavior composed of swimming, turning an...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/22.4.375

    authors: Valentincic T,Caprio J

    更新日期:1997-08-01 00:00:00

  • Bimodal (taste/tactile) fibers innervate the maxillary barbel in the channel catfish.

    abstract::Analysis of single fibers isolated from a branch of the facial/trigeminal complex innervating the maxillary barbel of the channel catfish, Ictalurus punctatus, indicated the existence of bimodal (taste/tactile) fibers. Of the 60 single fibers recorded, 14 (23%) responded to both taste (amino acid) and tactile stimulat...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/22.4.477

    authors: Ogawa K,Marui T,Caprio J

    更新日期:1997-08-01 00:00:00

  • Rapid classical conditioning of odor response in a physiological model for olfactory research, the tiger salamander.

    abstract::In recent years there have been a number of important advances in the understanding of cellular mechanisms related to olfactory function. Hypotheses regarding the complex relationships among odorant structure, physiological activity and behavioral outcome generated by these findings, however, remain largely untested d...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/22.3.277

    authors: Dorries KM,White J,Kauer JS

    更新日期:1997-06-01 00:00:00

  • Ontogeny of the solitary chemosensory cells in the zebrafish, Danio rerio.

    abstract::Secondary epidermal solitary chemosensory cells (SCCs) are widespread among the primary aquatic vertebrates. They resemble taste bud sensory cells in fine structure and may be innervated from facial or spinal nerves. According to previous studies, SCCs may constitute a water sampling system in the contexts of predator...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/22.2.111

    authors: Kotrschal K,Krautgartner WD,Hansen A

    更新日期:1997-04-01 00:00:00

  • Olfactory functions in Parkinson's disease and Alzheimer's disease.

    abstract::The aim of this investigation was to compare olfactory functions of patients suffering from Parkinson's disease (PD) and Alzheimer's disease (AD). Olfactory threshold, odor identification ability and odor memory performance were assessed in 21 non-demented PD patients and in 22 AD patients. Both patient groups were im...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/22.1.105

    authors: Lehrner JP,Brücke T,Dal-Bianco P,Gatterer G,Kryspin-Exner I

    更新日期:1997-02-01 00:00:00

  • Are odorant-binding proteins involved in odorant discrimination?

    abstract::Pheromone-sensitive sensilla trichodea of nine moth species belonging to six families and three superfamilies of Lepidoptera were immunolabelled with an antiserum against the pheromone-binding protein of Antheraea polyphemus. Strong immunolabelling of the sensillum lymph was observed in all long sensilla trichodea of ...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/21.6.719

    authors: Steinbrecht RA

    更新日期:1996-12-01 00:00:00

  • SW.B6-Soa(b) nontaster congenic strains completed and a sucrose octaacetate congenic quartet tested with other bitters.

    abstract::Ten SW.B6 SOA nontaster strains congenic with the SWR/J SOA taster inbred strain were bred via repeated backcross-intercross cycles, with selection for nontasting in each cycle. Preference ratio distributions and phenotypic proportions across cycles at 0.1 mM SOA were consistent with monogenic predictions. The SW.B6 m...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/21.5.507

    authors: Harder DB,Gannon KS,Whitney G

    更新日期:1996-10-01 00:00:00

  • Phagocytic cells in the taste buds of rat circumvallate papillae after denervation.

    abstract::Phagocytic cells in the taste buds of rat circumvallate papillae after the sectioning of bilateral glossopharyngeal nerves were examined by electron microscopy and immunohistochemistry. Electron micrographs taken 1 day after denervation revealed that flat-shaped cells were present just beneath the taste buds and that ...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/21.4.467

    authors: Suzuki Y,Takeda M,Obara N,Nagai Y

    更新日期:1996-08-01 00:00:00

  • Chemoreceptive control of feeding processes in hydra.

    abstract::Cnidarians are the simplest metazoans to exhibit satiety after feeding. When hydra are fed to repletion, they close their mouths and cease to capture prey. As feeding stops, contractions of the tentacles and body column increase. Our earlier experiments showed that a gel chromatographic fraction of prey substances inh...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/21.3.313

    authors: Grosvenor W,Rhoads DE,Kass-Simon G

    更新日期:1996-06-01 00:00:00

  • Anterior tongue stimulation with amiloride suppresses NaCl saltiness, but not citric acid sourness in humans.

    abstract::Suppression of the saltiness of NaCl solutions by amiloride, a sodium channel blocker, has previously been reported a number of times in humans. This suppression was seen with techniques that involved stimulation of small areas of the tongue. It was not certain, however, whether amiloride would suppress saltiness with...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/21.2.113

    authors: Tennissen AM,McCutcheon NB

    更新日期:1996-04-01 00:00:00

  • Detection of tastes in mixture with other tastes: issues of masking and aging.

    abstract::When one taste (masker) is strong enough, it can completely mask another task (target) of different quality. How strong the masker must be to do this depends on how strong the target is. As the target concentration is increased, the masking concentration must be increased, too, but in ever-increasing proportion. To qu...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/21.2.211

    authors: Stevens JC

    更新日期:1996-04-01 00:00:00

  • Switch and bait: probing the discriminative basis of odor identification via recognition memory.

    abstract::When people misidentify everyday odors, as they often do, their errors may conceivably lie in faulty perceptions or in faulty access to the names. Discussions of the matter usually focus on the latter, as if people had no problems with perceptual accuracy. (The problem of faulty access may get attention because its hi...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/21.1.35

    authors: Cain WS,Potts BC

    更新日期:1996-02-01 00:00:00

  • Amiloride is an ineffective conditioned stimulus in taste aversion learning.

    abstract::The present study demonstrated that 100 microM amiloride serves as an ineffective conditioned taste stimulus in a taste aversion paradigm. Even if amiloride has a detectable taste, it's unlikely that its behavioral effects in salt mixture experiments are due to its inherent taste quality. ...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/20.5.559

    authors: Markison S,Spector AC

    更新日期:1995-10-01 00:00:00

  • Taste sensitivity and aging: high incidence of decline revealed by repeated threshold measures.

    abstract::Contrary to what has often been said about the subject, decline in taste sensitivity with aging characterizes virtually everybody and is not the artificial result of averaging large losses of a minority with negligible losses of a majority. This assertion is supported by six repeated measures of sucrose thresholds in ...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/20.4.451

    authors: Stevens JC,Cruz LA,Hoffman JM,Patterson MQ

    更新日期:1995-08-01 00:00:00

  • Distinct projections of two populations of olfactory receptor axons in the antennal lobe of the sphinx moth Manduca sexta.

    abstract::The central projections of olfactory receptor cells associated with two distinct types of antennal sensilla in the sphinx moth Manduca sexta were revealed by anterograde staining. In both sexes, receptor axons that arise from sexually isomorphic, type-II trichoid sensilla (and possibly some basiconic sensilla) project...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/20.3.313

    authors: Christensen TA,Harrow ID,Cuzzocrea C,Randolph PW,Hildebrand JG

    更新日期:1995-06-01 00:00:00

  • Memory for brief, widely spaced odor presentations in the rat.

    abstract::Rats trained on a series of 16 novel 2-odor discrimination tasks using a 10-s intertrial interval (ITI) rapidly improved in performance and made only 0-3 errors by the end of the test series. They were then tested on other novel pairs of odors, but with a 10- and a 30-min interval between trials. There was no decremen...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/20.2.183

    authors: Lovelace CT,Slotnick BM

    更新日期:1995-04-01 00:00:00

  • Dopamine regulation of transcription factor-target interactions in rat striatum.

    abstract::Transcriptional regulation is an important mechanism by which neurons adapt to environmental stimuli. The indirect dopamine agonists, amphetamine and cocaine have been shown to induce expression of immediate early genes, such as c-fos, and neuropeptide genes, such as prodynorphin in the rat striatum. Here we show that...

    journal_title:Chemical senses

    pub_type: 杂志文章,评审

    doi:10.1093/chemse/20.2.257

    authors: Hyman SE,Cole RL,Konradi C,Kosofsky BE

    更新日期:1995-04-01 00:00:00

  • Porcine VEG proteins and tear prealbumins.

    abstract::Small soluble proteins, belonging to the lipocalin family are secreted in large amounts by tongue von Ebner's glands and lachrymal glands. In humans, the lingual protein, called VEG, and the lachrymal protein, called tear prealbumin, have shown identical cDNA sequences. In the pig, we have purified homodimeric protein...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/20.1.69

    authors: Garibotti M,Christiansen H,Schmale H,Pelosi P

    更新日期:1995-02-01 00:00:00

  • Olfactory responses of chum salmon to amino acids are independent of large differences in salt concentrations between fresh and sea water.

    abstract::In chum salmon captured at the coastal sea and the natal river, the magnitudes of the olfactory nerve responses to the amino acids after perfusion of the olfactory epithelium with artificial pond water (APW) were similar to those after perfusion with artificial sea water (ASW), although the concentrations of Na+, Cl- ...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/19.6.609

    authors: Shoji T,Fujita K,Ban M,Hiroi O,Ueda H,Kurihara K

    更新日期:1994-12-01 00:00:00

  • Mosaic analysis of the embryonic origin of taste buds.

    abstract::The embryonic origins of taste receptor cells have not been established experimentally. Although related receptor cells (e.g. hair cells of the inner ear, lateral line receptors) are known to arise from neurogenic ectoderm (e.g. neural crest or placodes), taste buds are described as arising from local epithelial cells...

    journal_title:Chemical senses

    pub_type: 杂志文章,评审

    doi:10.1093/chemse/19.6.725

    authors: Stone LM,Finger TE

    更新日期:1994-12-01 00:00:00

  • Histochemical localization of NADPH-diaphorase in the rat accessory olfactory bulb.

    abstract::The distribution of NADPH-diaphroase activity was examined in the accessory olfactory bulb of the rat using a direct histochemical technique. Labeled fibers and somata were found in all layers of the accessory olfactory bulb. The entire vomeronasal nerve and all vomeronasal glomeruli were strongly labeled, contrary to...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/19.5.413

    authors: Porteros A,Alonso JR,Arévalo R,García-Ojeda E,Crespo C,Aijón J

    更新日期:1994-10-01 00:00:00

  • Individual differences in the perceived intensity and quality of specific odors following self- and cross-adaptation.

    abstract::Adaptation techniques have traditionally been employed in sensory physiology and psychology to characterize afferent pathways and to dissect the quantitative and, to a lesser degree, the qualitative aspects of perception. We continue to explore the individual differences in olfactory capabilities among subjects initia...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/19.3.197

    authors: O'Connell RJ,Stevens DA,Zogby LM

    更新日期:1994-06-01 00:00:00

  • A model of the role of adaptation and disadaptation in olfactory receptor neurons: implications for the coding of temporal and intensity patterns in odor signals.

    abstract::Natural odors occur as turbulent plumes resulting in spatially and temporally variable odor signals at the chemoreceptor cells. Concentrations can fluctuate widely within discrete packets of odor and individual packets are very intermittent and unpredictable. Chemoreceptor cells display the temporally dynamic properti...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/19.1.71

    authors: Moore PA

    更新日期:1994-02-01 00:00:00

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